Melbourne Demons and Essendon Bombers have met 16 times — Melbourne Demons won 9, Essendon Bombers won 7, with 0 draws. Melbourne Demons leads the head-to-head with 9 victories from 16 meetings. A combined 2615 goals have been scored across these fixtures, averaging 163.44 per match (1253 for the home side, 1362 for the visitors). Both teams scored in 16 matches (100%). Over 2.5 goals landed in 16 games (100%), making it a fixture that tends to produce goals. The highest-scoring encounter finished 112–130 in .