San Francisco 49ers vs Los Angeles Chargers

San Francisco 49ers and Los Angeles Chargers have met 17 times — San Francisco 49ers won 12, Los Angeles Chargers won 5, with 0 draws. Their rivalry dates back to 2010. San Francisco 49ers leads the head-to-head with 12 victories from 17 meetings. A combined 696 goals have been scored across these fixtures, averaging 40.94 per match (401 for the home side, 295 for the visitors). Both teams scored in 17 matches (100%). Over 2.5 goals landed in 17 games (100%), making it a fixture that tends to produce goals. The highest-scoring encounter finished 17–41 in 2026.