San Francisco 49ers vs Arizona Cardinals

San Francisco 49ers and Arizona Cardinals have met 32 times — San Francisco 49ers won 18, Arizona Cardinals won 14, with 0 draws. Their rivalry dates back to 2010. San Francisco 49ers leads the head-to-head with 18 victories from 32 meetings. A combined 1445 goals have been scored across these fixtures, averaging 45.16 per match (780 for the home side, 665 for the visitors). Both teams scored in 32 matches (100%). Over 2.5 goals landed in 32 games (100%), making it a fixture that tends to produce goals. San Francisco 49ers are currently unbeaten in the last 3 meetings. The highest-scoring encounter finished 29–45 in 2023.