San Francisco 49ers vs Arizona Cardinals

San Francisco 49ers and Arizona Cardinals have met 31 times — San Francisco 49ers won 16, Arizona Cardinals won 15, with 0 draws. Their rivalry dates back to 2010. San Francisco 49ers leads the head-to-head with 16 victories from 31 meetings. A combined 1359 goals have been scored across these fixtures, averaging 43.84 per match (725 for the home side, 634 for the visitors). Both teams scored in 31 matches (100%). Over 2.5 goals landed in 31 games (100%), making it a fixture that tends to produce goals. The highest-scoring encounter finished 29–45 in 2023.