San Francisco 49ers vs Arizona Cardinals

San Francisco 49ers and Arizona Cardinals have met 31 times — San Francisco 49ers won 17, Arizona Cardinals won 14, with 0 draws. Their rivalry dates back to 2010. San Francisco 49ers leads the head-to-head with 17 victories from 31 meetings. A combined 1379 goals have been scored across these fixtures, averaging 44.48 per match (744 for the home side, 635 for the visitors). Both teams scored in 31 matches (100%). Over 2.5 goals landed in 31 games (100%), making it a fixture that tends to produce goals. The highest-scoring encounter finished 29–45 in 2023.